Like all medicines follow the instructions and all will be fine . after all that has happened in the last three years about jagging pigeons ( and I used to do them all at the same time) I have done them at different/ staggered times with a bottle opened fitted to my gun and returned to the fridge and reused for a few weeks . As long as the pigeons are quarantined for the time stated by the manufacturer all will be fine . IMO it's the pigeon fancier that causes the problem.