BeriMax Trichomonas is probably the most frequently found parasite in pigeons, but clinically disease is less often seen. The last 20 years no new drug has been introduced to cure this disease. In the middle of the '80, it was documented by researchers by the veterinary faculty in Utrecht, The Netherlands, that many of the Trichomonas strains were resistant to the most used drugs, like Spartrix, Ronidazol, Emtryl and Flagyl. Actually, all these drugs are chemically very similar, so a parasite resistant to one of them, would also be, or easily become, resistant to the other once. The reason for the development of resistance is the wrong use of medicines. Low doses in a short period (one or two days), kill the weakest parasites, but not the strongest. The result is more strong resistant parasites. Therefore many lofts are struggling with Trichomonas. The last years I have tested numerous substances for the effect against trichomonas. CITROMED was tested last year, and this citrus fruit product has a fairly good effect, but was not able to eradicate this parasite completely. Many chemicals, plant- and other natural extracts have been tested, and finally we have found a very effective remedy called BERIMAX. This is a yellow bitter pigment, chemically an alkaloid, which has a very good effect on the Trichomonas. We made a 10% solution, and form this solution we added 1 ml per litre of drinking water. The pigeons were treated in during 5 days, and then given clean tap water for 3 days. When the pigeons were tested for Trichomonas, 90 % were free from the parasite. After this we made a 20 % solution, buffered the solution, and gave 1 ml per litre drinking water. After only 10 hours, all the 4 test pigeons were free from the parasite when crop wash was examined under the microscope. These results were so good that we have conducted larger tests on a number of lofts, and we have been able to eradicate Trichomonas completely. Another positive effect of BERIMAX is that it is very active also against many common, but nasty bacteria like E. coli, Salmonella, Clostridium, and parasites like Giardia and Hexamita, commonly giving intestinal problems. We will also study the effect on coccidiosis and worm infections, and the results from this study will appear in Winning later this year or next year. But we will not stop the study here. Even important is to monitor the pigeons during the season, to find out if the medication has a positive effect of the breeding results or flight results. Also, the final formulation (strength), the most appropriate duration of treatment, the best package and other technical details have to be made before the product generally will be available. If somebody, any were in the world, want to participate in the final clinical study, this will be welcomed. BERIMAX will probably be distributed by Sinornis Pharma (www.sinornis.com) together with other pigeon health products. BERIMAX will initially not be considered as medicine, because the active compound is not on the medicine list, and the plants used are not considered as medicine plants. This means that the BERIMAX can be easily available for any pigeon fancier. It is a very interesting, but time also a time consuming and expensive process to develop new remedies. I hope BERIMAX will be a good alternative in the struggle against Trichomonas and probably other diseases in the future. \ BERIMAX forte. Product data sheet Origin: Berimax is a natural purified plant extract. Chemically it is an alkaloid and is a very bitter yellow pigment. This alkaloid is present in many specific plants found on all continents. The extraction and purification is complicated and can be carried out by CO2 extraction method. Purity is 98 %. Berimax contains 20 % purified plant extract. This is equivalent to 200 mg / ml. Biological properties: The plant extract of Berimax has the property to destroy single cell organisms like Trichomonas, Giardia, Hexamita parasites, but also bacteria like E. coli and Clostridium spp. This plant extract has also shown ability to inhibit cancer cells, and to protect liver cells against certain toxins. The plant extract of Berimax has also the ability to inhibit inflammations. Toxicity: The plant extract of Berimax is considered as non-toxic. However, taken in high doses can lead to intoxication. The lethal doses ( LD50 ) for rats is bout 1 gram per kg body weight, or 5 ml pure extract. Incompatibility: Berimax must not be mixed with any drug or water additives as we have seen flocculation and precipitation when mixed with e.g. acids, or medicines. Such visible chemical reactions might result in toxic compounds. Medical claims: No. Type of product: Nutraceutical. Liquid water soluble. Strong yellow colour and a bitter taste. 50 ml medical glass bottles. Use: General dose 5 mg per kg body weight. 1 ml is suitable for 40 kg bodyweight. Otherwise give 1 drop per 2 kg body weight. For very small animals dilute 1 ml in 9 ml of water, and give 1 or two drops. Oral administration. Horses 2 g once (=10 ml liquid) Cattle 3 g once (=15 ml liquid) Sheep and pigs 0,5 - 2,0 g once (= 2,5 ml liquid) Drinking water application for pigeons, poultry, birds* and rabbits. To kill Trichomonas and other single cell intestinal parasites, use 1 ml per litre of water. Give during 1 - 5 days. Up to 10 days. Warning: Use plastic gloves and disposable cloth when using this product due to strong yellow staining. Unnecessary contact with the product can give allergy (although not yet reported). *The product have been tested on poultry, European quail, domestic pigeons, canary, and some parrot and parakeet species and found safe. However, there might be species or individuals not tolerating this product well, and there might also exist until now undiscovered circumstances in housing, management, climate, nutrition or pathology which can result in adverse reactions by using this product. Allergy against this product can occur. This products have not been evaluated as medicine and can therefore not claim any specific medical properties. However experience and scientific literature have proven the efficacy and safety of this plant extract. Manufacturer and responsible company: Sinornis Pharma Ltd (Companies House No 4691134) Office 48, Imex Wansbeck Business Centre Rotary Park Way, Ashington, Northumberland, NE63 8QZ, England Research and sales office: Sinornis Pharma Ltd Norwegian Branch, Phone 0047 975 60 818 Fax 00 47 55 93 60 55, e-mail: sinornis@is.online.no web address: www.sinornis.com