DMG

[Guest]

Has anyone else used it. I used it last year and the difference in the condition of the birds was amazing, when they came back from hard races they still looked like they could go back.

[andy]

SBELBIN,

           GREAT STUFF, BUT THERES DMG & DMG......

[MsPigeon]

What is DMG?

[Guest]

DMG is basically the new wonder drug (been around for 40 years!!!) that pigeons can't win without. This is what I have on it, but note that it forms an advert for the stuff:

 

N, N-Dimethylglycine (DMG)

  

N, N-Dimethylglycine (DMG) is a versatile nutrient, accessory food factor and intermediary metabolite that can enable a person or animal to function at more optimum mental and physical level and aid the body in overcoming a number of adverse health conditions.  DMG is an intricate part of human metabolism and has been used in the health field as a nutritional supplement for over 25 years.  

  

The benefits of supplemental DMG are many:

 

Reduces Physical and Environmental Stress

Improves Oxygen Utilisation

Enhances Liver Function

Aids Cardiovascular Functions

Optimises Athletic Performance

Improves the Immune Response

Helps Improve Neurological Function

Possesses Anti-Inflamatory Properties

Enhances Anti-Viral, Anti-Bacterial and Anti-Tumour Defences

 

  

As a nutritional supplement, Dimethylglycine can improve physical and mental performance by helping the body adapt to the various forms of stress.  Athletes have been using DMG for years to improve stamina, reduce muscle cramping and enhance recovery from intense workouts.  University research and clinical studies demonstrates that DMG may be beneficial in helping the body overcome a number of health problems including cardiovascular disorders, inflammation, tumours, chronic fatigue syndrome and autism.  DMG may even retard the aging process because of its ability to reduce metabolic stress caused by poor oxygen availability (hypoxia), free radical damage and

a weakened immune system.  DMG can enhance the healing process for most health disorders as well as promote greater vitality, energy and performance.

  

Background

  

Dimethylglycine was widely studied in the Soviet Union in the ‘60’s as part of the Russian formula known as Calcium Pangamate.  Their studies indicated that DMG was beneficial to athletic performance, cardiovascular function, detoxification, skin problems and neurological function.  In one study, DMG was shown to protect the immune function of guinea pigs exposed to intense radiation.  DMG was found to aid cardiovascular function by reducing angina, high lipid and cholesterol levels, and high blood pressure as well as improve circulation to the extremities of the body.  The Soviet research on their DMG based formula demonstrated three basic properties:

  

Lipotropic effect (to protect the liver from fat infiltration)

Stimulation of oxygen utilisation

Detoxifying capacity  

 

  

Areas of DMG application

  

In their book, Prescription for Nutritional Healing, Dr. James Balch and Phyllis Balch, C.N.C., recommend DMG for over 35 different ailments, these include; Cardiovascular Problems, Glucose Metabolism, Inflammatory Conditions, Allergies, Chronic Fatigue, Tumours, Liver Disorders, Alcoholism and Drug Addiction, Respiratory Problems, Immune Response Deficiencies, Infections, Autism and Sports practice.

 

DMG is a normal, physiologically active nutrient found in low levels in such foods as cereal grains, beans and liver.  DMG is also produced in the body from Choline and Betaine as a cellular intermediate.  The liver rapidly converts DMG into other useful metabolites via a process known as oxidative dimethylation.  By this process, a methyl group of DMG can be made available for transmethylation reactions, a pathway which is essential to the production of many vital products of the cell.  Dr. J.W. Meduski of the University of Southern California has called DMG a “metabolic enhancer” because of the many ways DMG can improve cellular metabolism, especially under conditions of distress in the body.

 

  

Absorption and Storage

  

Dimethylglycine is very effectively absorbed from the digestive tract, including the oral cavity.  Sublingual ingestion of DMG provides effective and rapid absorption, effects of which are frequently evident within 20 minutes after taking the product.

 

The amino acid transfer complex for transferring DMG across the intestinal wall has been identified and is reported.  All indications are that DMG is metabolised rapidly by the liver into one and two carbon units and therefore the body does not store appreciable amounts of the nutrient.

 

  

Sports Practice and Athletic Use

  

The value of DMG as a nutrient and metabolic enhancer was first observed in the area of athletic performance.  DMG has long been used by athletes to improve overall performance and endurance, to enhance oxygen utilisation and to improve recovery of muscles after strenuous exercise.  It has been shown in a number of athlete and animal studies over the past 20 years that DMG specifically improves stamina and cardiovascular function in the body.

 

Thomas Pipes has reported in the Physicians and Sports Medicine Journal that Dimethylglycine significantly improved performance in a group of track and field athletes.  The DMG group showed an increase of 27.5% in VO2 Max and of 23.6% in time to exhaustion as compared to the placebo group.  DMG’s apparent ergogenic (energy enhancing) effects could be due to a number of factors, including better oxygen utilisation and cellular respiration, reduced lactic acid build-up, and enhanced carbohydrate and lipid metabolism.

 

A 1982 study by Levine and Myhre and published in Equine Practice showed DMG’s rapid ability to reduce a horse’s lactic acid level as compared to controls.  The authors reported over a five-fold decrease in lactate level build-up for the test animals as compared to controls.

 

Robert Cator, DVM at the Panhandle Regional Veterinary Clinic, which confirmed the results of the Equine Practice study, did another study.  Thoroughbreds were checked for speed and blood lactate levels with and without DMG at 210 heartbeats per minute.  The results show greater speed and a lower blood lactate level when DMG was part of the horse’s diet.

 

Potter and Moffitt also reported on DMG’s lactic acid lowering effect in a study which they did in 1985 at Texas A&M.  When horses were supplemented with DMG at the rate of 1.6 mg/kg, there was a significant reduction in blood lactic acid concentration after strenuous exercise on a treadmill.  This dosage equates to approximately one serving of 750 mg of DMG for a 1,200-1,400 lb horse.

 

The mechanisms of how DMG improves oxygen utilisation and reduces lactic acid accumulation are not clear, but its effectiveness in improving performance and recovery time from strenuous exercise is well established.  This is supported by the paper published in Canine Practice by Cannon and Kendall showing that racing greyhounds that were supplemented with DMG had improved racing times and better recovery from the previous day’s training or racing.

 

Meduski and co-workers at the University of Southern California conducted experiments with rabbits to monitor the effect of Dimethylglycine on lactic acid production under hypoxic conditions.  New Zealand White rabbits were exposed to severe surgical stress, a condition known to increase blood lactate in animals.  Those animals that received DMG showed markedly decreased levels of lactic acid in their blood compared to control.  

 

Meduski also reported improved oxygen uptake of rats which were on Dimethylglycine supplementation and exposed to low oxygen (8%) environment.  The DMG fed rats showed better adaptation to hypoxia than did the controls by actually utilising more oxygen from the low oxygen environment.

 

A New York City marathon club under the direction of Dr. Gary Null did a six-month study, where they carefully compared the use of DMG in a marathon to a previous race where it was not used.  The improvements were impressive.  In the second race the runners took 500 mg DMG before the race and then followed by 250 mg for every four miles covered.  The marathoners reported much less exhaustion as compared to the previous race.  Based upon compiled statistics, better race times were obtained along with improved stamina, muscle and body recovery, and especially the reduction of cramping and fatigue from the 18th to the 26th mile mark in the marathon.

 

The evidence that DMG can enhance the performance of athletes is quite strong.  The research, along with actual field evaluation, shows that DMG is beneficial to endurance athletes (runners, team sports) as well as short-timed events (weight lifters, sprinters).  Not only will DMG help in overall performance and recovery, but it will also boost the immune defence of the individual athlete and make them less susceptible to infections or other illnesses.

 

  

Immune Response Enhancement

  

An individual’s immune response is a person’s defence against foreign substances (antigens, pathogens).  Its role is to seek out, identify and destroy those invading substances, which can cause disease or health problems.  The immune system is made up of different cell types (B-cells, T-cells, macrophages) immune complexes and molecular products of B and T cells (antibodies from B-cells, cytokines from T-cells).  Macrophages are large scavenger lymphocytes (white blood cells), which engulf and kill the invader.  Antibodies are proteins which react with specific germs and alert T-cells (lymphocytes) to identify and attack the foreign substance.  Together these cells and molecular products work to destroy and eliminate cancer cells, bacteria and viruses which are disease causing.  Factors that weaken the immune system and decrease the immune response include age, metabolic or genetic disorders, microbial infestations, stress, nutritional deficiencies, many drugs and most degenerative diseases.  The stronger the immune system, the greater the immune response will be against disease causing agents.  This results in fewer symptoms of infection and greater probability of avoiding sickness.

A strong immune system is an important part of staying healthy, avoiding serious illness and fighting off exposure to pathogens that may occur.  Dimethylglycine (DMG) is a nutritional factor that can strengthen a person’s immune system and bring about a more effective response against any antigen (foreign substance).  Dr. Charles Graber and his research team first discovered this in 1978 at the Medical University of South Carolina.

  

 

Cardiovascular System  

  

Dimethylglycine supplementation has been found very beneficial for circulation and cardiovascular problems.  DMG enhances oxygen delivery to the heart and improves several characteristics of the blood.  

 

According to a symposium conducted in Moscow in 1964 (USSR Academy of Sciences and the Institute of Biological and Medical Chemistry), the principal field of DMG application in trials conducted at over 20 clinics was in the treatment of cardiovascular disorders.  The DMG formula was marketed as Calcium Pangamate, but careful assessment of the patent and scientific literature has demonstrated that Dimethylglycine was the active ingredient in the orally administered product.

  

The studies reported major improvements in the areas of arteriosclerosis, artherosclerosis, coronary circulation and myocardial function, angina pectoris and high blood pressure upon administration of DMG.

Good results were obtained on daily doses of Dimethylglycine from 50 mg to 90 mg.  The principal mode of action to which the improvements were ascribed centered on DMG’s ability to decrease hypoxia (low oxygen availability) to the various tissues, to improve various oxidative processes in the body, and to normalise lipid and carbohydrate metabolism.

 

  

Carbohydrate Metabolism  

  

There is good evidence that DMG may enhance carbohydrate metabolism.  There have been many individual reports from physicians who have attested to DMG’s value in lowering blood sugar levels in diabetic patients. Problems resulting from impaired circulation, including gangrene, pain in the lower extremities, wounds and ulcers on the legs and feet, all responded well to DMG supplementation.

  

Detoxification and Liver Support

  

Dimethylglycine is beneficial in support of liver metabolism and detoxification.  By improving oxygen utilisation, DMG can help eliminate hypoxia to the tissues and aid in the elimination of toxins from the blood stream.  Dr. Carl Pfieffer of the Bio-Brain Center in Princeton, NJ reported success in using DMG to reduce elevated histamine levels in certain patients.  This is probably achieved by increasing the transmethylation pathway and making more methyl groups available for detoxification of neuro toxic amines.  Patients undergoing either chemical or drug detoxification would benefit from DMG supplementation (500 to 1000 mg) to improve cellular metabolism for increased energy levels and improved detoxification.

  

Autism

  

There is a growing body of evidence that DMG is beneficial for individuals with autism.  Autism is a biological brain disorder of unknown causes that results in a wide range of puzzling and disturbing social and personal behaviour patterns.  Two studies have demonstrated that DMG can modify and improve the behaviour, social interaction, verbal communication and disturbing activities of autistic children.  Significant improvements were seen.

  

 

Conclusion

  

Dimethylglycine (DMG) is a versatile health potentiating and healing nutrient that can be used to maintain good health, enhance performance and productivity as well as aid the body in the healing and restoration process.  This Technical Bulletin has only touched the surface of the many areas where DMG has been found to be beneficial to the immune response, detoxification, mental and physical performance, enhancement to cellular metabolism and to many other specific areas as mentioned in this article.  When DMG is combined with other beneficial nutritional and therapeutic food factors, such as Perna (Green Lipped Mussel) additional synergistic effects may result.  DMG can be safely combined with any nutritional or therapeutic product without negative side effects.

 

Dimethylglycine is a time-tested, scientifically proven and verifiable nutritional supplement that brings about greater vitality, good health and cellular regeneration.  Continued research with this marvellous nutrient will reveal even more about how DMG can be used to combat  the stress and the health problems that affect most people.  Dimethylglycine is available in a 125 mg sublingual tablet in Health Food Stores under the brand name, FoodScience Aangamik™ DMG.

 

 

 

So basically, its produced by the body in the normal digestion process, AND avialable in grains!!!!

 

 

[Guest]

Agree Andy, the stuff I used was the pure stuff, but ive been told a lot of companies cut it with Glucose, that isnt as effective.

[blue bar]

how much do you use on pigeons and how often  and how easy is it to get hold off

[Guest]

I started using it last year 2 weeks b4 our channel racing, and gave it mon, tues, wed, and thurs, it states on the tub to give it every day, but I like to give clear water on a friday. Its easy to get hold of it in England, I dont know about in New Zealand, I was recently told that DMG for greyhounds is better as its the pure stuff. Its no wonder drug, its just Vit B15, but is often called the Unfair advantage. If you read the BHW, the scribe Bilco always goes on about it, and in one of his reports he said he had once had a bad cough and tried a bit of DMG himself, and his cough disappeared overnight.

[Guest]

Sbelbin, I note what you say, but my experience was different. In 2005 I'd decided on aviform ultimate containing multivits, dmg, anti-canker / cocci / worms and drinking water sanitation, twice per week in the drinker, to be upped to 5 times a week during racing (which I refused to do, similar reasons as yours, and stuck at twice a week).

 

Persevered with the stuff Jan - May. Basically couldn't see a blind bit of difference in my birds, or their performances, and stopped using it from 1st/2nd week in May. Bird's best performances occurred in the early weeks of June ... after I stopped using the stuff. (Er.. that is relatively speaking: performances were not bad rather than really f*ing bad!!!!         )

 

I note what you say about Bilco's article. Saw it, and if you read it again, you'll see that his reasoning makes absolutely no sense (gazing at the sun for too long?) not unless he breaths through his a**.

 

He was after all the same guy that promoted DMG from almost his first article for the BHW, 'can't HOPE to win without it',  etc etc.

[Guest]

Bruno, I can really only go by the difference in the birds condition and ability to recover so fast after a race, when I started using it, which was during the race season as more of a boost. From your post you were using it Jan to May, which is B4 the season has even begun, so really cant see how you can really say that you have tested it. The weeks I used it my birds massively improved, which obviously I dont know 100% that it was the DMG, but it did seem to coincide with it.

[ray]

Sbelbin, I've heard of DMG but nobody uses it.  At least that's what they say.  They say there is two different kinds, one with glucose and one without.  Is it on the carton or is there a certain make that I need?  I know lots of lads who use glucose but as this is my first year of racing i would like to give DMG a try.  Could you recommend a make of DMG without glucose and where to buy it as you seem to think it's good stuff?

 

Thanks mate

 

Yours in sport

 

Ray

[celtic]

Ray,

Shelbin mentioned that there is a type of DMG for greyounds possibly ?

GREYHOUND DIRECT 0800 371 591 may be able to help .

Cheers Celtic

[Guest]

Alright Ray, I have just got some at blackpool which is the pure stuff, i.e. no glucose, if you had said I could have got you some. If you get the BHW and look at the advertisements, there is a company that sells the pure stuff. I would say if its your first year, I would keep it all natural though and learn about the birds B4 you start with supplement etc. as you start to instictively know when they need a boost after a few years racing.

[ray]

yeh your right i am all natural this year and next, thanks for the advice as i would not know what i was looking for

[celtic]

Did you try that number ray ?

[ray]

celtic i looked on there web site nothing mentioned on it, i typed in there search engine but nothing found, i found pigeon dmg in homing world i might give it a try but as this is my first year and flying natural, i wont no what im looking for to see if i should use it or not thanks celtic

[juleia]

Aangamik DMG  is a great supplement. I have not had to take any steroids since I have been taking this. My breathing is better now and my energy level is back to normal, my taste is better, my attitude is better, and I just feel great

[Guest TAMMY_1]

I started using it last year 2 weeks b4 our channel racing, and gave it mon, tues, wed, and thurs, it states on the tub to give it every day, but I like to give clear water on a friday. Its easy to get hold of it in England, I dont know about in New Zealand, I was recently told that DMG for greyhounds is better as its the pure stuff. Its no wonder drug, its just Vit B15, but is often called the Unfair advantage. If you read the BHW, the scribe Bilco always goes on about it, and in one of his reports he said he had once had a bad cough and tried a bit of DMG himself, and his cough disappeared overnight.[/quote]

 

you do not believe all you read   tried it on my pigeons for a season and came to the conclusion it was an expensive waste of money ( yes another one ), the birds never performed any better than the previous year, think half these wonder performance enhancers are all in the fanciers imagination that they do any good, but I have fallen for them at some point as well and have finally got a great health programme to work with all year round using mainly natural things and they will not empty my pocket as much as the likes of DMG.

[Guest shadow]

very expensive waste of money ??)